#Red4Research Blog: Susanna Maria, Deputy Nurse Manager, Cardiovascular and Diabetes Research at MRI

#Red4Research brings together all those participating, supporting, and undertaking research. To celebrate this year’s #Red4Research Day, Susanna Maria, Deputy Nurse Manager for Cardiovascular and Diabetes Research at Manchester Royal Infirmary (MRI) – part of Manchester University NHS Foundation Trust (MFT), shares her pride in being part of research that is transforming peoples’ lives.

Being part of research, I am at the forefront of medical discovery, and it is about more than just conducting studies; it is also about contributing to advancements that can improve the lives of countless individuals and making a real difference in the health and well-being of our community. 

As Deputy Nurse Manager in the Cardiovascular and Diabetes Research Unit at the MRI, I am proud to be part of a team dedicated to advancing patient care through innovative, specialist, research.

 Our Research Team 

In my role I accompany our participants throughout their research journey, from recruitment all the way to end of the research study. As part of this team, I am fortunate to regularly witness how our collective efforts transform lives – not just through scientific discovery, also through compassionate, patient-centred care. 

Our team is a tapestry of diverse talents, each thread contributing to a shared vision: improving patient outcomes through collaborative research. From doctors and clinical research nurses to study coordinators, specialist nurses, research practitioners, laboratory and pharmacy technicians, and Principal/Sub Investigators, every member plays a crucial role. This collective effort fosters an environment where innovation thrives, and patient care remains the top priority.

We focus on advancing treatments for conditions that negatively affect the body’s blood vessels (vascular diseases). The studies we currently lead aim to explore new therapies that could significantly improve vascular health, particularly in patients with complex conditions.

Among the many highlights is our work in the CORALEEF studies. High cholesterol (too much of a fatty substance called cholesterol in the blood) is a growing concern globally, contributing significantly to the risk of heart problems or stroke. Statins have long been the standard treatment. However, a newer class of drugs, PCSK9 inhibitors, has emerged as a promising alternative for those who need more intensive cholesterol-lowering options. At present these new drugs are only available as injectables. CORALEEF is exploring the first PCSK9 inhibitor taken as a pill, to help lower cholesterol. This new oral option could benefit patients by offering a convenient once-daily dose that is easier to fit into daily life.

Early research suggests the treatment could more effectively slow or stop progression of the condition, helping patients maintain their quality of life longer. Also, patients may experience fewer or less severe side effects compared to current options, making the treatment easier to stay with over time.

Our amazing participants

Our participants bring more than just their medical history – they bring hope, trust, and a willingness to contribute to something greater than themselves.

Their involvement is not just about advancing science, it is about making a tangible difference in the lives of others. Their courage to participate, often in the face of uncertainty, fuels our commitment to conducting research that is ethical, compassionate, and impactful.

The vital role of families

Families are the unsung heroes of clinical research. Their support, encouragement, and involvement are crucial to the success of our studies. They provide emotional and sometimes practical support to participants and often serve as advocates for their loved ones. Their dedication ensures that participants feel supported and valued throughout their research journey. Looking ahead, we remain focused on what matters most: The patients, their experiences, feedback, and outcomes guide our research endeavours.

By maintaining a patient-centred approach, we ensure that our work not only contributes to scientific knowledge but also makes a tangible difference in the lives of those we serve. Also, as we reflect on our achievements, we are energized by the knowledge that our work is far from done.

On #Red4Research Day I want to express my gratitude to our participants, their families, and everyone who makes research possible.

It is collaboration that makes research successful – research participants, professionals, partners and more, all collectively working together.

Together we will continue to make a lasting impact on healthcare – one study, one participant, and one breakthrough at a time.