Meet the Team

Principal Investigators

Professor Tim Felton

Tim Felton is Professor of Respiratory and Critical Care Medicine in the Division of Infection, Immunity and Respiratory Medicine at the University of Manchester and Honorary Consultant in Intensive Care and Respiratory Medicine at Wythenshawe Hospital part of Manchester University NHS Foundation Trust. He is Director of the NIHR HealthTech Research Centre in Emergency and Acute Care and an Associate Medical Director for Research and Innovation. He qualified in medicine in 1999 at the University of Nottingham. Prof Felton undertook his training in Respiratory and Intensive Care Medicine in the Northwest of England and in Sydney, Australia. He completed an MRC Clinical Research Training Fellowship and was awarded his PhD in anti-infective pharmacology by The University of Manchester in 2014. His research interests are in developing diagnostic-led antimicrobial stewardship and precision medicine strategies for patients with respiratory tract infection and sepsis to improve clinical outcomes and suppress emergence of antimicrobial resistance.

Professor Stephen Fowler

Stephen Fowler is a professor of respiratory medicine at the University of Manchester and honorary consultant physician at Manchester University NHS Foundation Trust. His clinical and research interests lie in the diagnosis, classification and management of airways disease, principally asthma and associated conditions such as inducible laryngeal obstruction and breathing pattern disorders.  He is adviser for the 2024 NICE “Diagnosis, monitoring and chronic asthma management” guideline, and co-lead for the NIHR-Manchester Respiratory BRC. He is investigating novel non-invasive biomarkers for phenotyping inflammatory and infectious lung disease, through the detection and analysis of volatile molecules in exhaled breath.

Professor Brian Keevil

Brian Keevil is a Consultant Clinical Scientist at Manchester University Hospitals Foundation Trust. He is Clinical Lead for the Clinical Biochemistry Department at Wythenshawe hospital and director of the clinical mass spectrometry unit.

His research interests involve the development and introduction of novel mass spectrometry methods for the measurement of therapeutic drugs and steroids. His laboratory has pioneered the use of these techniques many of which are used to underpin routine clinical services and collaborative international research projects.

Steroids have been a particular interest, and the laboratory performs a wide range of steroid assays in blood urine and saliva samples. These methods are being used to refine existing endocrine protocols and to explore the use of newer novel steroids such as the 11 oxygenated steroids in the diagnosis and management of endocrine conditions. He is the recipient of a UKRI scholars grant to investigate the use of salivary cortisone in the investigation of adrenal disease.

He has published more than 240 peer reviewed publications and is an honorary Professor at the University of Manchester.