Clinical research studies

We currently support a number of clinical research studies, including:

  • ALIFE 2 – Low-molecular-weight heparin to increase the chance of live birth in women with recurrent miscarriage and inherited thrombophilia
  • Couples having IVF treatment – The generation of human embryonic stem cells for clinical use and Sperm, Egg and Embryo Research
  • DETECT – DEveloping Tests for Endometrial Cancer detection
  • FUTURE – a randomised control trial to evaluate the cost effectiveness of urodynamic investigations in management of  overactive bladder symptoms
  • Gem3 – a double blinded controlled trial aimed at understanding if patients presenting with ectopic pregnancies that will have treatment with Methotrexate could benefit from having a top-up of Gefitinib tablets to prevent the necessity of returning to hospital for further treatment versus placebo
  • NEST study – Clinical Evaluation of Daily Application of Nestorone® (NES) and Testosterone (T) Combination Gel for Male Contraception
  • Pelvic Vein Study – a randomised controlled trial that tries to understand if the reason of chronic pelvic pain in women is the incompetence of the Pelvic Vein and explores ways of treating the Incompetent Vein if this is observed in the participants
  • PROTECTOR – Preventing ovarian cancer through early excision of tubes and late ovarian removal 
  • RoboQol – An Evaluation Of The Impact Of Mode Of Surgery On Patient Centred Outcomes In Gynaecological Cancer
  • SHAPE – A randomised trial comparing radical hysterectomy and pelvic node dissection vs simple hysterectomy and pelvic node dissection in patients with low-risk early-stage cervical cancer
  • Sperm Research in Cancer Treatment – An investigation of the potential for human sperm cells to detect and target human cancer cells with chemotherapeutic drugs
  • TOPSY – a randomised control trial to assess the clinical and cost-effectiveness of self-management of vaginal pessaries compared to standard care to improve quality of life

For more information about these studies and other research in the area of gynaecology please contact gynaecology.research@mft.nhs.uk or 0161 701 4699