Clinical research studies

We currently support a number of clinical research studies, including:

  • ALIFE 2 – Low-molecular-weight heparin to increase the chance of live birth in women with recurrent miscarriage and inherited thrombophilia
  • Arquer – a study aimed at understanding if certain cancer cells are detectable in patients with ovarian and endometrial cancer with the aid of the Arquer`s Diagnostics system on various samples collected from our participants
  • Couples having IVF treatment – The generation of human embryonic stem cells for clinical use and Sperm, Egg and Embryo Research
  • DETECT – DEveloping Tests for Endometrial Cancer detection
  • E-Freeze – comparing 2 methods of embryo transfer
  • Endometrial Scratch – to assess the effectiveness of local endometrial scratch for those having IVF
  • FUTURE – a randomised control trial to evaluate the cost effectiveness of urodynamic investigations in management of  overactive bladder symptoms
  • Gapp2 – a double blinded randomised controlled trial investigating if Gabapentin vs placebo can be useful in controlling the levels of pain in ladies with chronic pelvic pain, in women that have had a negative laparoscopy (no gynaecology cause for pain was observed on procedure)
  • Gem3 – a double blinded controlled trial aimed at understanding if patients presenting with ectopic pregnancies that will have treatment with Methotrexate could benefit from having a top-up of Gefitinib tablets to prevent the necessity of returning to hospital for further treatment versus placebo
  • HORIZONS – Exploring the recovery of health and well-being in adults diagnosed with cancer. We are recruiting to ovarian, endometrial, cervix, vulval, Non-Hodgkin Lymphoma, and Wythenshawe to breast cancers. It aims at understanding the impact of cancer diagnosis and treatment on every day life
  • LATITUDE – an observational study assessing the effectiveness of the urethral bulking agent Bulkamid as a first line treatment for Stress Urinary Incontinence
  • Pelvic Vein Study – a randomised controlled trial that tries to understand if the reason of chronic pelvic pain in women is the incompetence of the Pelvic Vein and explores ways of treating the Incompetent Vein if this is observed in the participants
  • PRE-EMPT – Preventing Recurrence of Endometriosis by Means of long acting Progestogen Therapy
  • RoboQol – An Evaluation Of The Impact Of Mode Of Surgery On Patient Centred Outcomes In Gynaecological Cancer
  • SHAPE – A randomised trial comparing radical hysterectomy and pelvic node dissection vs simple hysterectomy and pelvic node dissection in patients with low-risk early-stage cervical cancer
  • STATEC– a randomised trial that tries to understand if lymphadenectomy, used to restrict adjuvant therapy, vs non-lymphadenectomy  results in a non-inferior survival rate as compared to adjuvant therapy given to all women with high risk apparent stage 1 endometrial cancer
  • TOPSY – a randomised control trial to assess the clinical and cost-effectiveness of self-management of vaginal pessaries compared to standard care to improve quality of life

For more information about these studies and other research in the area of gynaecology please contact or 0161 701 4699