Clinical research studies
We currently support a number of clinical research studies in areas including:
Autism Spectrum Disorder (ASD)
- iBASIS – To assess the impact and fesibility of an infancy intervention in siblings of children already diagnosed with an autism spectrum disorder.
- Pre-school Autism Communication Trial (PACT) – From 2006-2010 PACT tested a parent-mediated communication-based intervention for young children with autism. The trial was a major scientific success and constitutes one of the largest autism intervention studies completed internationally.
- PACT 7-11 Follow Up – Follow-up study of all the families who were involved in the PACT trial.
- PACT G – A new large trial funded by NIHR and MRC which looks at the generalisation of the PACT treatment model into schools and homes with the aim of further improving effectiveness
- SimvAstatin in Neurofibromatosis Type 1-Autism (SANTA) – Looking at the use of the drug Simvastatin in children with NF1 and Autism Spectrum Disorders.
Mental Health Clinical Trials
- Self-Harm Intervention Family Therapy (SHIFT) – A randomised controlled trial of family therapy vs. treatment as usual for young people seen after second or subsequent episodes of self-harm.
Attachment and Social Development
- Social Outcomes and Early Life Experiences Study (SOCiAL) – To improve understanding of how and why children who experience adversity in their early lives sometimes go on to show emotional and behavioural difficulties that persist despite subsequent improvements in their care.