Sphincter Morphology & Function in External Rectal Prolapse
An Exploratory Study to Investigate the Relationship Between the Morphology and the Physiological Function of the Anal Sphincter in Patients with External Rectal Prolapse Before and After Surgical Intervention
- Hospital – Speciality: Wythenshawe Hospital – Colorectal
- Study type: Basic Science
Summary
We know that some patients with rectal prolapse experience problems with incontinence of stools before and/or after surgery, but the reason for this is not fully understood. Incontinence can have a negative impact on patients’ quality of
life, and therefore improving our understanding of why this happens is important.
In this study we will measure the morphology (thickness & shape), strength and function of the sphincter muscle with specialist tests (using thin tubes placed inside the back passage), and ask patients to complete questionnaires to assess for symptoms of ‘anorectal dysfunction’ (incontinence of stools or constipation) before and after surgery.
By investigating the relationship between the anal sphincter muscle morphology and the strength and function of the muscle, we will develop a better understanding of how important a role changes in the sphincter muscle play in the cause of incontinence in patients with prolapse, both before and after surgery for this condition
Participant group
Patients due to undergo surgical repair for rectal prolapse.
Participant approach
The researcher will access the electronic patient records of potentially eligible patients, to determine if the inclusion criteria are satisfied. Eligible patients will be approached by the researcher. Patient’s will either be approached face-to-face if identified in advance of their clinic appointment, or by telephone/post if identified after their clinic appointment or from the surgical waiting list.
Study open date and expected length
Opened: August 2025
Expected end date: August 2028
Results
Pending – this study is still active.
Contact details
Telephone number: 0161 291 6654
Email address: matthew.davenport2@mft.nhs.uk
- IRAS number: 350642
